Many, many old quilts combine handwork with machine sewing. :)
As soon as our great-great-grandmothers got sewing machines, they used them for piecing and quilting.
You can almost feel the relief when you look at the back of an old quilt - the blocks are hand-sewn, but then they are sashed or sewn together by machine. It's like the maker was saying, "Finally, I can get all these blocks put together and make something out of them!" :)