Gads, I don't do that anymore really.
But one year recently at Quilt Camp in the Desert - an almost week long series of different quilting classes held here in Phoenix at the end of January - they had someone teaching hand quilting without a hoop (or frame.) I sat in on the class briefly but holding the needle was too much for me to do for long.
So, now I know of quilters who do a variety of hand quilting: hoop, frame, and neither.
ali