I recently made a "manly" quilt, using the Bistro line from Moda. You can see it at:
http://www.quiltingboard.com/posts/list/15110.page
It had coffee-themed designs in the fabric, so it was still a bit whimsical. The blues, greens and the light tans were really nice together, so maybe use something similar? I would stay away from the really dark prints in the line, if this is for a bedroom. Happy quilting!