I have a 26" Innova on a 10 ft frame. If I had the room I would have gone on a bigger frame. I love, love, love my Innova. I think it is the best bang for the buck LA on the market. You won't regret getting it.
As far as between the 22" or the 26" if you can pay the little extra go for the bigger throat. I don't use all the quilting space I have simply because I can't reach that far but I love having it.