I have a serger, use it for everything but quilting. I have seen instructions in serging books, for how to make quilts that are usually small sized, and durable.... like baby quilts or something. The seams are all serged and they are super durable. Lots of tugging, pulling, washing and use. But for heirloom quilting? No.
Love my serger. Love my various sewing machines. Wish I had a 26' x 40' room to put it all in! lol.