What a terrible feeling this must be! I've been noticing that my kids (35, 33 and 30 yr old kids) don't really take much interest in all the quilts and quilting going on in my house. I think, from their perspective, this is just what Mom's 'into' right now. Because of that lack of interest, I've decided not to gift any family members with quilts right now. I will make them each a quilt, however, and save it to be given to them when I'm no longer around. I know that it will mean a lot more to them then. For now, I look forward to quilting for donations (like to senior citizens in a home who don't get any visitors). Maybe this sounds morbid, but just know that my kids aren't really interested right now, and by saving them a quilt for later might be more meaningful.
My 2 cents worth.