I love wool! Warmer in winter & cooler in summer. Needles wonderfully. I know that it is more expencive but I try to get it on sale.
I would also like to let you know what I learned when my oldest DS thought he wanted to be a fireman. The class he took said that man made fibers will melt to the skin if there is a fire. If I make a quilt or blanket to be used on a bed I want natural fibers. I don't like to hand quilt with cotton so that leaves wool. I do plan to make some wall hangings so I'll use something with lower loft for these, maybe even flannel. I've also made some throws from fleece but I make sure that these are not used on beds.