You could do something like english paper piecing (grandmothers flower garden type of thing) have a look a Jinny Beyer's web site
http://www.jinnybeyer.com/ as she is a hand piecer so her patterns should work, or something like tumbling blocks or I did this wallhanging for my son, this is entirely hand pieced
http://www.quiltingboard.com/picture...s-t163579.html