I have a HQ Sweet 16 in the sitdown version, not on a frame. I use lots of different types of thread - SoFine, King Tut, Aurifil (probably my favorite because the varigations are so nice), Gutterman, and some miscellaneous others. For bobbins I used to use the same as the top, but now I almost always use a SuperBob prewound. I think it is a 60 weight or so, and I really like it. It is a real bother to have to change a bobbin in the middle of quilting, and the prewounds hold a lot of thread! I have a collection of 10 different basic colors, and I generally can use one of them successfully.
Pam