you can quilt any quilt with an (as you go) method if you so choose-
you can quilt each block individually then join them with sashing strips-
you can construct your quilt into rows- horizontal or vertical -then quilt each section before joining them together-
you can construct the quilt into 1/4's or what ever manageable size panal/piece- quilt it then join them- any and all of the techniques are done all the time. just decide which method seems to be the one that will work for you and go for it-
there are plenty of tutorials on quilt as you go-
elenor burns has a pattern out called the 6 hour quilt- it is a good quilt as you go method
then there is always the cotton theory technique
the raggy quilt technique (which you can always do to join the quilted squares- then fold the seams in upon themselves and stitch them down instead of clipping/ragging)
there are u-tube videos, tutorials, and patterns- or
since it is your project you can simply decide how you want to do it and go for it.