If you want to do basic sewing/patchwork any basic machine will do. You just have to find one you like (it's like test-driving a car). If you want to venture into quilting, I would recommend getting one that has a large throat area. The regular machines make it harder to fit the quilts for actual quilting.
My must haves are needle up/down, motor speed selector, needle position left/right, good light, large throat, large table. I fell in love with the drop-in bobbin, automatic threader and the automatic foot lifter on my Baby Lock so that is my brand of choice. However, I know that Janome, Bernina, Brother, and most Pfaff users are very loyal to their brand as well.