Practice, practice and practice!!!
Start with a small size 25x25 inch and increase from there.
If quilt is hanging off the table or cabinet, then it will pull on fabric which will cause issues.
Spray basting will cause skipped stitching. Has happen to me on Janome TB30 as well as my Singer 15-90.
I do NOT use spray basting now because of that-plus bad for your lungs.
Re-read Leah Day's tips.
Read Diane Gaudynski "Guide to Machine Quilting".
Adjust your tension dial to make the stitching look nice and pretty.
Keep bobbin area clean of threads and lint.
Play with speed of machine while moving fabric in straight line and curves; take note of where issues occur and make adjustment by either speeding up or slowing down.
RE Watch Leah Day's tutorials.
Practice, Practice, and Practice!!