Funny ... hubby and I are planning a similar trip, I'm a little further north in Illinois.
Assume you will be taking 57 south to 24?
If so, that will take you right through Paducah!! In which case not only can you go to Hancock's of Paducah (enormous!), and Eleanor Burns Quilt in a Day (small), but you should also visit the AQS museum while your there.
Enjoy!!