you will need to use a lightweight stablizer (interfacing) with the silks---it will make a huge difference in cutting and stitching- use a new, thin, sharp needle- a new blade in your cutter.
Dream Orient is a great choice for batting. it is a bamboo/silk blend- fabulous to work with
i have successfully mixed silks and cottons- in a quilt with wonderful outcome.
the only thing i worried about was iron temp...don't want to scorch the silks-
a good fusable, lightweight stablizer and you are ready to jump into your project! enjoy the process & be sure to share pictures