You must be reading my mind. I have been thinking about the same thing. I found this on-line magazine that has a wealth of quilt trips; bus, train, ship. All you have to do is sign up and you can read the magazine free.
http://www.quiltposium.com/
My sister and I would love to take the New England/Canada cruise, but we live in California. So tack on a $800 round trip airfare and it gets too expensive.