I have learned one very important thing during the years since I have started hand quilting: there is no "wrong" or "right". What works best for you can be bad for me. Every hand quilter seems to have her/his own favourites in battings, needles, threads, fabrics, gadgets and notions etc. and the best thing to find out what works for you is to try it! Well, it will probably takes some time to work it out but you will find your own way.
My personal favourits are #11 John James Betweens, a low loft batting without a scrim (Hobbs 80/20, Legacy 80/20, Wool), YLI Hand Quilting Thread and light weight fabrics like P&B Color Spectrum. I only load one single stitch on my needle, I quilt in a hoop on a floor stand and I don't use a thimble at all. But this is just my personal way of hand quilting....