if it is in very good condition then there is nothing wrong with putting quilt in washing machine with a little oxyclean...let it soak for about thirty minutes, spin and drain. then run normal wash cycle with no detergent and then when finished put it in the clothes dryer unless you are afraid of it shrinking badly. i make and sell quilts and most of what i make have alot of handwork etc... before the quilt is sold, i do a good wash and dry of the quilt-it is like a final test to see if what i produce will hold up. i do use a color catcher in the wash load just in case of colors running. this should take out cigarette/cigar smoke smell as well as discoloration from the smoke...also, do not ever store a quilt in plastic...use a cotton pillowcase or two and refold quilt every now and then.