I think you might want to test some of the fabrics with a wet Q-tip or damp cloth to get an idea of how much bleeding to expect. With the fabrics having not been previously washed, there could be quite a bit, so Color Catchers can help pick up the loose dye so that it doesn't land on other areas. If you used cotton batting, you can expect shrinkage there that might not match the shrinkage in the fabric. Cool water, low agitation, and avoiding heat in the dryer will all minimize the bad effects. If you don't mind the extra work, you can wash it by hand in the bathtub and lay out to dry on towels on a hard surface floor after squeezing (not wringing) out the excess water.
I agree that freshening can be done by hanging the quilt outside, but eventually you will have to face the task of washing the quilt if it is being used regularly.
Best wishes!
Dayle