I have the Janome 300E embroidery machine. It is a great machine. I bought the machine, brought it home and within 30 minutes I was doing my first embroidery. I have used my embroidery machine a lot and have never had a problem with it. If I had it to do all over again, I do believe I would buy the 350 mostly for the thread cutter! I prefer having the embroidery machine separate from my sewing machine so that I can use them at the same time.
Good luck and I hope this helps.