There are a couple of situations where pressing the seams open are an issue. If you're planning to stitch in the ditch - you will be stitching only over the threads that connect the top together, not very secure. If you use a batting that is not made from long fibers (less expensive) there is a tendency, over time, for those short fibers to work their way up & out, bearding, to make the quilt appear fuzzy. Otherwise - go for it!