I just made a chemo quilt for a coworker using the 1600 inch pattern (1 - moda jelly roll [Butterfly garden]) with borders and wrote comforting words of the quilt. She loves it and is displaying it when not using it.
Since it was a surprise, I just observed her to see what colors to use, but asking is always good. I did it large lap with a 50/50 bamboo and cotton batting, which made is lighter.