I also want to stress that kittens can be spayed and neutered at around 2 pounds. That is our clinic's limit. They do absolutely fine. All mine were done as kittens and i have had zero issues. My males have never sprayed and their urine is not smelly. I think it has to do with the fact they never developed a lot of the male hormones due to pediatric spay. I had more problems years ago when they waiting until the cats were older.