Yes, I always wash my quilts after I finish them. I don't want the recipient to have any surprises down the road. Most of my quilts are charity quilts, so they must be clean. Especially for QFK or other kid's charities, I use All Free & Clear detergent and then use a dryer sheet in the dryer, also All Free & Clear. When gifting quilts you should always be careful about scents because of the possibility of allergies with the person receiving them.