I have used them in the center of star blocks, as the window in attic windows, when printed larger (say 12x16) as the center medallion in a quilt. I tested washing one photograph to make certain it would remain printed. I just tossed it in with my regular laundry load, including towels, and it came out beautifully. I figured I'd try the harshest test--I'm sure none of the recipients would ever wash a quilt that way so I could be certain there'd be no problems. I print the photos on muslin and use them as they are, without backing, just like any other cotton.