What am I missing? It seems your fabric is wide enough, and long enough, that you could piece it with a single seam, either across or down (45+45 = 90 - more than wide enough for your widest edge). Then, the only consideration is likely how you are quilting. I understand that long armers prefer the seam to go across the back, rather than vertical. Makes the pieces roll better on the frame.
Editted to add:
Another thing to consider - how is it being used (now that I think I understand the 2 seam question). A bed quilt for a single bed, you wouldn't want to seam in the middle, because then that would be right on top of the sleeper. But if it's for a double bed being used for 2, then a single seam is best (between the sleepers) because seams closer to the edges would be on top of the people.
Last edited by kristakz; 08-09-2012 at 01:57 PM.