I don't have Factor 5. That's what they thought at first when I landed in the hospital. Ends up I have Factor 2, which isn't as bad, but I do have to be careful. No horomones ever (apparently the birth control the idiots a the gyn decided to put me on caused the first clot - even after I told them about my dad's history of clots, varicose viens and such). Also have to be careful when I travel. In the car, have to stop at least every 2 hours to get out and move around. Flying I have to give myself an injection before and after. Also have to have all sorts of precautions and stuff for any kind of surgery. Kind of a scary thing. Sometimes I forget I have it, and other times it jumps up in my face, like the other day with my leg. Was glad it turned out to be nothing, but better safe than sorry!!