I have found that SOME of the lower priced cottons seem to be as nice or nicer - in my opinion - than SOME of the LQS lines.
There are several LQS lines that I don't care about at all - one line has very clever prints/designs, but some of the fabrics seem loosely woven with coarse threads. Another line seems sort of thin, flimsy, and stretchy to me. Another line (it may have improved since I bought a lot of those fabrics) had issues with fading.
But it does come down to personal preference - not everyone loves the heft of Kona cottons, for example.