I have never used spray adhesive for number of reasons including cost. I have yet to baste an entire large quilt sandwich with Elmers but I think that if price is not an issue spray may be easier to apply. I will (I hope) baste my latest quilt sometimes this week using Elmer's and I will post my experience. Wish me luck. It is certainly bigger than qayg blocks I did but the principle is the same. Longer drying period maybe?