Yes I have felt that way. I was in a depression and only going deeper. My friends and family finally talked me into getting help. I went to my doctor and she put me on anti-depressants. I've been on them a few times and always go off and end up depressed again. My brain just doesn't produce enough seritonin. Needless to say, I won't be going off them again. It's nice to have my life back. It's not a shameful thing to be on anti-depressants.