Start by checking your library for quilting books. What you are describing is a fairly ambitious project. You need to understand how to sew 12" blocks together, and you need to decide whether you want to print your own photos on fabric or whether you prefer to send them to a place that will put them on fabric for you. There are pro's and con's to both. If you decide to do it yourself, you need to learn the different methodologies. The Bubble Jet Set is one way of doing it, or you can purchase ready-to-print sheets of fabric at the store. You can Google to find more information on photo transfer to fabric methods. It's very important to know which type of printer to use with which type of fabric prep, if you are doing it yourself. It's also important to know which fabrics take photos the best (effects are different on different fabrics).
You will also need to decide whether you want the quilt hand quilted or machine quilted. Again, you can pay someone to do this or you can learn how to do it yourself. Machine quilting involves more learning, but books from the library should help with that.