are you talking about cotton/poly fabric? or batting? or thread?...
people use cotton/poly blends all the time---yes even in quilts---
it wears like steel- is great for kids quilts, utility quilts that will be used/abused/ laundered often-
some people love using it
it can also be used for home dec items, table toppers, runners, placemats, curtains/drapes
if you simply don't like the fabric you can always donate it or pass it on .