let me tell you my simple little story. Made a simple string lap quilt out of beige, brown, dark brown and black fabric, used a dark brown backing. As the lap quilt was on the small size, I went into my box of pieces of batting, found two that would give me the size I would need, sewed then together and sandwiched my quilt. During my FMQ 'heard' my needle at times not sounding real happy, then it would stop.....when finished, looked at the back on half of the backing I had 'pokies' and half I didn't....you guessed it, when I sewed my batting together, I sewed one piece up side down......So yes it does make a difference and I have the backing to prove it.