I'm one of those hand quilters that uses Warm & Natural with no problems. I get small, consistent stitches with no issues. And after washing, the quilt has that (to me) nice crinkly look. I also use Roxanne needles for hand quilting. That will be another decision you'll have to make. Try several different brands of both with samples. Mark them as to batting brand and try several different needles in each one and mark it some fashion - different color threads - so you know which needle/batting combo gives you the look you want.