I use Warm & Natural pretty much exclusively -- I'm a more traditional quilter and like the way my quilts look after washing....wrinkly. If you like the slightly more puffy look and not quite so much shrinkage, I'd go with the other. Both are great products -- depends of what you like after washing. I don't pay much attention to how far to quilt between as I tend to quilt closer anyway, but you need to be aware of what the package says. I just quilt closer because I like how it looks and I like insurance!