I belong to 4 guilds. Two fairly small ones and two bigger ones. One of the small guilds has just 22 members, the other small guild has maybe 30 members. The two bigger guilds have right around 100 members.
The smaller guilds don't have big name speakers but they both have some very talented members that give the occasional class. The big guilds have a big name quilter once a year or so.
All of the guilds do some charity work of one kind or another.
I highly recommend joining a guild in your area. You might even have to go for a year before people start to get to know you!