I use fleece alot for quilt backs & I treat it the same as flannel or cotton. I prewash everything; lay it face down on the floor & tape the edges flat; lay my warm & natural on it & smooth it out; lay the quilt top on this & smooth it out & safety pin it my fists width apart; it takes time but it works. I quilt it the same way as any other quilt, it's not a race, so stitch slow enough for the walking foot to feed everything through at the same time; however I do not like dense panto type quilting, I stitch in the ditch & do a little free motion quilting approx. 4 or 5 inches apart. My quilts are still nice & soft & cuddly, and they are warm. Seems like we all have different experiences with our quilts, it's good to get lots of opinions & then try & find out what works for you.