I use Organ about 99.9% of the time - I can't remember ever having any trouble with them.
Recently, I bought some Orange brand and whaddaya know - they're just as good!
The only problem with the "generic" type brands is that they're not going to have the specialty needles like Schmetz has - wing needles, twins of different widths, topstitch, etc.
But since I've got "old gal" machines, I pretty much use sharps for everything anyway.