Now I may be a radical BUT I do clean my sewing room after I finish a quilt. That way all the pieces of the finished quilt are out of the way and I have a clean slate to work with. I do try to only have 2 (or at the most 3 pieces) working at the same time. One at the hand sewing part, one on the machine and one in planning. BUT I still clean after each completion. (I have also decided after each quilt, anything small than a fat quarter is getting cut into 2 1/2" squares and filed by color.)