I agree with Jingle's observation that people will wash their quilts like their sheets and just as often (or almost). So that's how I wash mine. I use a top loader, cold water, regular detergent, then the dryer. But have only gone as big as queen sized. that one is hand quilted. So far I haven't had any issues. On a new one going to someone I use some color catchers. I am not a pre washer, except for flannel.