Selena, i tried the MSM that i got in Minnesota and it turned my knee (after I rubbed it on) red with dots. burned a lot. i was highly allergic to Sulphur. didn't bother my Husband though.
I am too old now not to worry about things that can cause me to have a stroke or heart attack , or worse. so i don't take Nsaids anymore. they can only be taken for a few years anyway. I"m down to two meds a day now and doing OK.
good luck.