sure....tons of times...all the time....i am always working on hand projects- my 'Hex' project, grandmother's flower gardens, tumbling blocks, cathedral windows, wool applique.... the list goes on & on...then the project reaches the point where the hand work is done & i put it all together with the machine...
my wool 'Backyard Gathering' quilt is all wool hand appliqued blocks/borders- machine pieced & quilted
a majority of my quilts contain hand work along with machine parts.
[ATTACH=CONFIG]396535[/ATTACH]created this basket of flowers one weekend while laying on the couch with a cracked ankle up on pillows, watching Bond movies- then machine quilted & bound it when i could use my foot again.