I'm not sure I'd include the boyfriend. At 20 (as is my daughter), he may be gone before the quilt is finished. I'd save him for the (bite my tongue) wedding quilt.
Does she read? Something with a favorite childhood book might be nice.
Maybe a silly phrase she said as a child.
Grandparents?
The list is really endless when you get started thinking about it. This could be a really fun quilt to make.