Rolling a quilt makes it too stiff...sort of like a "log"...I do more of an "accordian fold" and secure that, and "puddle" the part of the quilt that is in front of me.
Do you have your machine set into a cabinet, so you have a nice flat surface, or if you don't have a cabinet, do you have a large sewing surface (acrylic table) that fits onto your machine? The larger flat surface you can have, the better. As others have said, surround yourself with tables, ironing board lowered, etc.