I normally don't use it either...sometimes for handbags, etc. This quilt is going to be used more as a throw so I thought it might be ok to use the fusible.
I really should try to take a picture of the clamps that my husband got me because they are the best thing since sliced bread in my opinion. You center your backing, clamp it down on the lip of your cutting table...center your batting, reclamp it down...center your top, reclamp it down. It keeps everything from shifting. Then I used my iron on the center area, unclamped it and moved it over and finished pressing each side.
I then turned the quilt over and pressed the back and only had to make a couple of really small adjustments.