I would think about how the quilt will be used and how often it will be laundered before spending big bucks on batting. If the fabric you are using is loosely woven you will have to worry about bearding. If you are machine quilting you will need a walking foot and the kind of batting doesn't really matter except for the bulk you will have to get under the machine. As a handquilter I love the way cotton batting " hands". Unfortuneatly it makes for a heavy quilt to sleep under. Blends or poly are now my first pick for any project.