Yes you can reuse the same piece several times, it will loose its stickyness, like you I did 2" squares to start with, all scrappy, I made them into blocks using 12 squares across and down as I wasn't sure if I was going to break up the blocks with sashing, in the end I just joined them all together, came in very handy when I had to sit around waiting for my daughters doing there various activities and of course travelling in the car - hope you have fun with it