You didn't say exactly what it is you're wanting to do.
Have you "tested" the waters to know if there is a need for this business?
What will you need to take in each month for you to deam it a success?
For years (30+) I have done alterations for people. There was a time when that's all I did, no outside job. Thankfully, I had insurance through the hubby's job. All that has changed now. No hubby. Have to buy my own insurance. Taxes, etc. That's when the alteration business went to part-time while I worked outside the home. Still no benefits with any of the jobs.
Lots for you to consider. Hope whatever you decide, that you find peace.