I can't say I have a 'favorite' color combination. Many times a color will catch my eye and I find coordinating colors to go with. For instance, I will be making at-shirt quilt for a nephew and I asked my sister (his mom) about colors. She said Marine blue and red. Went to my LQS after work to look around and found Kona solids in what I thought would work, but solid is boring. I asked my sister if the color had to be solid or if I could go tone-on-tone. I was tickled when she said tone-on-tone..."Quilts need texture!" I'll go back in a day or two and look some more, because I saw some beautiful possibilities!