I have FMQ a large quilt on my regular sewing machine, so it is possible but not easy. As long as you aren't planning to do any kind of 'design' in the quilting that requires turning the quilt around in the middle of the design, you will be able to do it. One thing I discovered - when you are FMQ you don't HAVE to move the quilt from the front of the machine to the back. There are times when I had difficulty fitting the quilt wadded up in the small space so I quilted 'backwards' - bringing the quilt from the back of the machine to the front.