Hi Steve, First I would decide which designs to use, then use an A4 page -or graph paper-to make a mini pattern, draw a 'box' to mark the size of each design and include all measurements. You should be able to use this to mark off all sections on your fabric on the frame. (make sure your fabric is larger than you want the finished quilt) and measure constantly. This is how I will go about making my wholecloth quilt - when I get around to doing it.
Hope this helps,
Cheers, Gay